LIMK1/2 inhibitor LIMKi 3 suppresses porcine oocyte maturation

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LIMK1/2 inhibitor LIMKi 3 suppresses porcine oocyte maturation

LIMKi 3 is a specific selective LIMK inhibitor against LIMK1 and LIMK2, while LIMK1 and LIMK2 are the main regulators of actin cytoskeleton to participate in many cell activities. However, the effect of LIMKi 3 in porcine oocyte meiosis is still unclear. The present study was designed to investigate the effects of LIMKi 3 and potential regulatory role of LIMK1/2 on porcine oocyte meiotic matura...

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ژورنال

عنوان ژورنال: PeerJ

سال: 2016

ISSN: 2167-8359

DOI: 10.7717/peerj.2553